MSI Isolated Components: The isolated component method copies shared files (typically DLLs) into an application's folder instead of a shared location. The application then uses these files instead of global ones, preventing modifications made by other applications from affecting the shared files.

Depending on your scenario, you might want core isolation memory integrity to be on or off. For instance, since the feature can affect performance, it is ideal to switch it off when you want to use your Windows PC for gaming.